If I thought I wouldn’t game at all, I’m pretty sure my next PC would be a NUC, simply because they are so small and adorable. And you can get a full PC without any real compromises–you can have fast storage, lots of memory, a good port selection. And it can sit silently and adorably on the desk, where those ports are easy to get to.
I will likely build a new, bigger PC with a full-size video card in the near-future to replace my current, aging machine. But I might go ahead and then build a NUC as a secondary/experimental PC. I might even try a zany Hackintosh build, so I can have that Mac experience, but with a good keyboard.